DeMaMech: EU-Japan Collaboration in Higher Education Student Exchange Program

Offer of Research Topic

Offer from	University	University of Tokyo
	Faculty/Department/Institute	Graduate School of Engineering, Department of Precision Engineering
	Group Name	Biomedical Engineering
Research Theme		Ensemble Recording from Neuronal Networks
Brief Explanation		Highly parallel, spatio–temporal processing of signals is a fundamental feature of biological systems, perhaps most clearly in the network of neurons in the central nervous system. The microelectrode array (MEA) technique is one of the most promising methods to visualize spatially distributed neuronal signals. In this study, ensemble recording is carried out using cultured cortical neurons on MEAs.
Research Steps		1. Literature survey (one month) 2. Culturing neuronal cells on electrode-array substrates (one month) 3. Multi-site recording of neuronal activity (two months) 4. Analysis of recorded data including spike detection, spike sorting, correlation analysis(one month)
Period		5 months, but can be extended as a 10-month project.
Necessary Background, Knowledge, Skills		Fundamental knowledge about biological information processing. If necessary, some references can be specified.
Further Information		http://bme.pe.u-tokyo.ac.jp/index_e.html
Contact Person		Prof. Dr. Yasuhiko Jimbo (jimbo@miki.pe.u-tokyo.ac.jp)